Depends what I'm using it for. I love all my guitars, and enjoy them all.
Which do I pick up the most often? My acoustic, because it is the most-convenient, as I don't have to plug it in or anything; just pick it up and go.
But, I do love playing loud every now and then. So I love my electrics, too. My Strat is better for nastier solos, my Tele is better for the twangy stuff.
And, my (acoustic) resonator is great for some of the more-fingerpick-y stuff.